{"id":666,"date":"2021-11-20T12:58:36","date_gmt":"2021-11-20T12:58:36","guid":{"rendered":"https:\/\/2024.ar-calendar.ro\/octombrie\/"},"modified":"2023-12-06T10:34:46","modified_gmt":"2023-12-06T10:34:46","slug":"oktober","status":"publish","type":"post","link":"https:\/\/2024.ar-calendar.ro\/hu\/oktober\/","title":{"rendered":"Okt\u00f3ber"},"content":{"rendered":"

[vc_row equal_height=”yes” content_placement=”middle” el_class=”month-hero”][vc_column width=”1\/2″][vc_custom_heading text=”Okt\u00f3ber” font_container=”tag:h4|text_align:left|color:%2375518f” use_theme_fonts=”yes” el_class=”month-title mobile”][vc_single_image image=”418″ img_size=”full” alignment=”center” image_hovers=”false” lazy_loading=”true”][\/vc_column][vc_column width=”1\/2″][vc_custom_heading text=”Okt\u00f3ber” font_container=”tag:h4|text_align:left|color:%2375518f” use_theme_fonts=”yes” el_class=”month-title desktop”][vc_custom_heading text=”George Emil” font_container=”tag:h3|text_align:left|color:%2375518f” use_theme_fonts=”yes”][vc_custom_heading text=”Palade” font_container=”tag:h1|text_align:left” use_theme_fonts=”yes”][\/vc_column][\/vc_row][vc_row el_class=”month-work”][vc_column][vc_custom_heading text=”\u00c9lete” use_theme_fonts=”yes”][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]George Emil Palade 1912. november 19-\u00e9n sz\u00fcletett J\u00e1szv\u00e1s\u00e1ron. Az \u00e1ltal\u00e1nos \u00e9s k\u00f6z\u00e9piskol\u00e1t sz\u00fcl\u0151v\u00e1ros\u00e1ban v\u00e9gezte, majd 1930-ban apja tan\u00e1csa ellen\u00e9re, beiratkozott a bukaresti Carol Davila Orvostudom\u00e1nyi Egyetemre. Itt, m\u00e1r di\u00e1kkor\u00e1ban becsatlakozott az anat\u00f3miai laborat\u00f3rium munk\u00e1j\u00e1ba. Hat\u00e9ves klinikai gyakorlat ut\u00e1n, 1940-ben megkapta az orvosdoktori c\u00edmet.<\/p>\n

Az egyetem befejezt\u00e9vel r\u00f6vid ideig belgy\u00f3gy\u00e1szati tev\u00e9kenys\u00e9get folytatott, majd visszat\u00e9rt az anat\u00f3mi\u00e1hoz. A m\u00e1sodik vil\u00e1gh\u00e1bor\u00faban a rom\u00e1n hadsereg katonaorvosak\u00e9nt szolg\u00e1lt, ezt k\u00f6vet\u0151en pedig 1946-ban az Amerikai Egyes\u00fclt \u00c1llamokba utazott tov\u00e1bbfejleszteni tud\u00e1s\u00e1t. New York-ban tal\u00e1lkozott Albert Claude-al, aki megh\u00edvta a Rockefeller Orvosi Kutat\u00f3int\u00e9zetbe.<\/p>\n

1973-ban otthagyta a Rockefeller Egyetemet \u00e9s a Yale-en kezdett el dolgozni, majd 1990-t\u0151l nyugd\u00edjba vonul\u00e1s\u00e1ig, a Kaliforniai Egyetem professzora volt.<\/p>\n

Palade, 2008. okt\u00f3ber 8-\u00e1n hunyt el a kaliforniai Del Mar-ban, 95 \u00e9ves kor\u00e1ban.[\/vc_column_text][\/vc_column][\/vc_row][vc_row el_class=”month-work”][vc_column][vc_custom_heading text=”Munk\u00e1ss\u00e1ga” use_theme_fonts=”yes”][vc_row_inner][vc_column_inner width=”1\/3″][vc_single_image image=”349″ img_size=”full” alignment=”center”][\/vc_column_inner][vc_column_inner width=”2\/3″][vc_column_text]George Emil Palade, Albert Claude-al kar\u00f6ltve, els\u0151sorban a sz\u00f6vetek \u00e9s sejtek elektronmikroszk\u00f3pos vizsg\u00e1lat\u00e1val foglalkozott. Az egyik legkiemelked\u0151bb szakmai hozz\u00e1j\u00e1rul\u00e1sa a sejtfelsz\u00edn, a membr\u00e1nok \u00e9s a sejtv\u00e1z kutat\u00e1sa volt. Palade felt\u00e1rta a mitokondrium fel\u00e9p\u00edt\u00e9s\u00e9t, kimutatta, hogy az addig mitokondrium-fragmentumoknak tartott mikrosz\u00f3m\u00e1k a sejt bels\u0151 transzportrendszer\u00e9hez tartoznak. \u0150 fedezte fel a ribosz\u00f3m\u00e1kat. Tanulm\u00e1nyozta az idegsejtek k\u00f6z\u00f6tti szinapszisok szerkezet\u00e9t \u00e9s \u00faj laborat\u00f3riumi technik\u00e1kat dolgozott ki a sz\u00f6vetek mintael\u0151k\u00e9sz\u00edt\u00e9s\u00e9ben \u00e9s a sejtek frakcion\u00e1l\u00f3 centrifug\u00e1l\u00e1s\u00e1ban.<\/p>\n

1950-ben publik\u00e1lt tanulm\u00e1ny\u00e1ban r\u00e9szletesen \u00edrt a ribosz\u00f3m\u00e1k \u00e9s az endoplazmatikus retikulum szerep\u00e9r\u0151l a sejtfeh\u00e9rj\u00e9k szint\u00e9zis\u00e9ben. Ezenfel\u00fcl, autoradiogr\u00e1fi\u00e1s technik\u00e1val k\u00f6vette a termel\u0151d\u0151 feh\u00e9rj\u00e9k sz\u00f6veteken bel\u00fcli \u00fatj\u00e1t, \u00e9s foglalkozott a hajsz\u00e1lerek fal\u00e1nak \u00e1tereszt\u0151k\u00e9pess\u00e9g\u00e9vel. 1964-ben a sv\u00e1jci Ewald Weibellel k\u00f6z\u00f6sen, le\u00edrta a v\u00e9rerek bels\u0151 fal\u00e1nak sejtjeiben, a rakt\u00e1roz\u00f3 funkci\u00f3kat ell\u00e1t\u00f3 Weibel-Palade testeket.<\/p>\n

P\u00e1ly\u00e1ja sor\u00e1n, George Emil Palade sz\u00e1mos d\u00edjban \u00e9s elismer\u00e9sben r\u00e9szes\u00fclt, 1974-ben pedig megkapta a fiziol\u00f3giai \u00e9s orvostudom\u00e1nyi Nobel-d\u00edjat is. Munk\u00e1ss\u00e1ga forradalmas\u00edtotta a sejtkutat\u00e1st \u00e9s hozz\u00e1j\u00e1rult a modern biol\u00f3gia m\u00e9lyebb meg\u00e9rt\u00e9s\u00e9hez.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row equal_height=”yes” content_placement=”middle” el_class=”month-hero”][vc_column width=”1\/2″][vc_custom_heading text=”Okt\u00f3ber” font_container=”tag:h4|text_align:left|color:%2375518f” use_theme_fonts=”yes” el_class=”month-title mobile”][vc_single_image image=”418″ img_size=”full” alignment=”center” image_hovers=”false” lazy_loading=”true”][\/vc_column][vc_column width=”1\/2″][vc_custom_heading text=”Okt\u00f3ber” font_container=”tag:h4|text_align:left|color:%2375518f” use_theme_fonts=”yes” el_class=”month-title desktop”][vc_custom_heading text=”George Emil” font_container=”tag:h3|text_align:left|color:%2375518f” use_theme_fonts=”yes”][vc_custom_heading text=”Palade” font_container=”tag:h1|text_align:left” use_theme_fonts=”yes”][\/vc_column][\/vc_row][vc_row el_class=”month-work”][vc_column][vc_custom_heading text=”\u00c9lete” use_theme_fonts=”yes”][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]George Emil Palade 1912. november 19-\u00e9n sz\u00fcletett J\u00e1szv\u00e1s\u00e1ron. Az \u00e1ltal\u00e1nos \u00e9s k\u00f6z\u00e9piskol\u00e1t sz\u00fcl\u0151v\u00e1ros\u00e1ban v\u00e9gezte, majd 1930-ban apja tan\u00e1csa ellen\u00e9re, beiratkozott a bukaresti Carol Davila Orvostudom\u00e1nyi…<\/p>\n","protected":false},"author":1,"featured_media":448,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-666","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized-hu","category-4","description-off"],"acf":[],"_links":{"self":[{"href":"https:\/\/2024.ar-calendar.ro\/hu\/wp-json\/wp\/v2\/posts\/666","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/2024.ar-calendar.ro\/hu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/2024.ar-calendar.ro\/hu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/2024.ar-calendar.ro\/hu\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/2024.ar-calendar.ro\/hu\/wp-json\/wp\/v2\/comments?post=666"}],"version-history":[{"count":5,"href":"https:\/\/2024.ar-calendar.ro\/hu\/wp-json\/wp\/v2\/posts\/666\/revisions"}],"predecessor-version":[{"id":878,"href":"https:\/\/2024.ar-calendar.ro\/hu\/wp-json\/wp\/v2\/posts\/666\/revisions\/878"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/2024.ar-calendar.ro\/hu\/wp-json\/wp\/v2\/media\/448"}],"wp:attachment":[{"href":"https:\/\/2024.ar-calendar.ro\/hu\/wp-json\/wp\/v2\/media?parent=666"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/2024.ar-calendar.ro\/hu\/wp-json\/wp\/v2\/categories?post=666"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/2024.ar-calendar.ro\/hu\/wp-json\/wp\/v2\/tags?post=666"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}